Description

1(3H)-Isobenzofuranone, 5-Bromo-3-Hydroxy- is a specialized brominated and hydroxylated derivative of isobenzofuranone, serving as a high-value synthetic intermediate. This compound is critical for constructing complex molecular architectures in advanced organic synthesis due to its reactive functional groups. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Its precise structure offers a versatile handle for further chemical modifications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those requiring brominated aromatic or heterocyclic cores.
• Agrochemical Research: Used in developing new herbicides, fungicides, and pesticides where the bromo-hydroxy substitution pattern can influence biological activity.
• Material Science Precursor: Serves as a monomer or starting material for synthesizing specialized polymers and advanced organic materials.
• Dye and Pigment Synthesis: Intermediate in the production of complex organic dyes and high-performance pigments.
• Academic & Contract Research: Essential reagent for methodological development and exploratory chemistry in university and CRO laboratories.
• Ligand and Catalyst Development: Used to create novel chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Item	Detail
Product Name	1(3H)-Isobenzofuranone, 5-Bromo-3-Hydroxy-
CAS No.	102126-71-6
Molecular Formula	C8H5BrO3
Molecular Weight	229.03 g/mol
Synonyms	5-Bromo-3-hydroxy-1(3H)-isobenzofuranone; 5-Bromo-3-hydroxyphthalide; 3-Hydroxy-5-bromophthalide; 5-Bromo-3-hydroxylphthalide; Bromohydroxyphthalide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-hydroxyphthalide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); handle and store under inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Area Percent)
Purity (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.