Description

(8S,9S,10S,13S,14S)-10-(Azidomethyl)-13-Methyl-2,6,7,8,9,11,12,14,15,16-Decahydro-1H-Cyclopenta[A]Phenanthrene-3,17-Dione is a high-purity, advanced steroid-based synthetic intermediate featuring a reactive azidomethyl functional group. This compound is critically important for pharmaceutical research and development, serving as a versatile building block for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology industries seeking to develop new steroid derivatives or labeled compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Click Chemistry Substrate: The azide group enables efficient conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and probe development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new biological activities of modified steroid scaffolds.
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for target molecules.
• Biochemical Tool Development: Can be utilized to create affinity probes or labeled analogs for studying steroid hormone receptors and metabolic pathways.
• Academic Research: Employed in universities and research institutes for synthetic organic chemistry projects and methodology development.

Basic Information

Product Name	(8S,9S,10S,13S,14S)-10-(Azidomethyl)-13-Methyl-2,6,7,8,9,11,12,14,15,16-Decahydro-1H-Cyclopenta[A]Phenanthrene-3,17-Dione
CAS No.	102053-40-7
Molecular Formula	C20H25N3O2
Molecular Weight	339.44 g/mol
Synonyms	10-Azidomethyl-13-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione; 10-Azidomethyl-13-methyl-3,17-dioxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene; Steroid Azide Intermediate; 3,17-Dioxo-10-azidomethyl-13-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and identity confirmation are available for each lot. Our quality protocols are designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep container tightly sealed in a dry, well-ventilated place. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0% Any single impurity ≤1.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.