Description

4-(Bromomethyl)Benzoylformate is a versatile brominated aromatic ester, a key synthetic intermediate in advanced organic chemistry. Its value lies in the reactive bromomethyl group, which facilitates efficient carbon-carbon bond formation and functional group transformations under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators, where the benzoylformate moiety can be incorporated into bioactive structures.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of functionalized monomers and polymers, contributing to the development of advanced materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized to create tagged or modified molecules for studying biological pathways and protein interactions.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in exploratory organic synthesis and method development.

Basic Information

Product Name	4-(Bromomethyl)Benzoylformate
CAS No.	102047-01-8
Molecular Formula	C10H9BrO3
Molecular Weight	257.08 g/mol
Synonyms	4-(Bromomethyl)benzoylformic acid methyl ester; Methyl 4-(bromomethyl)benzoylformate; α-Oxo-4-(bromomethyl)benzeneacetic acid methyl ester; Benzeneacetic acid, α-oxo-4-(bromomethyl)-, methyl ester; (4-Bromomethylphenyl)(oxo)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)Benzoylformate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.