Description

1H-1,2,4-Triazole,1-[[Tris(1-Methylethyl)Silyl]Methyl]-(9Ci) is a specialized organosilicon-protected triazole derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a protected intermediate for the controlled introduction of the 1,2,4-triazole moiety, which is a privileged scaffold in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-purity, functionalized heterocycles for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the 1,2,4-triazole core is pharmacologically active.
• Agrochemical Synthesis: Used in the research and development of new fungicides, herbicides, and plant growth regulators that incorporate triazole chemistry.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of advanced polymers, metal-organic frameworks (MOFs), and other functional materials where its silyl group allows for further functionalization.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes to study biological processes and interactions.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in custom organic synthesis and novel methodology development.

Basic Information

Product Name	1H-1,2,4-Triazole,1-[[Tris(1-Methylethyl)Silyl]Methyl]-(9Ci)
CAS No.	101804-56-2
Molecular Formula	C12H25N3Si
Molecular Weight	239.43 g/mol
Synonyms	1-[(Triisopropylsilyl)methyl]-1H-1,2,4-triazole; 1-(Triisopropylsilylmethyl)-1,2,4-triazole; 1-[[Tris(1-methylethyl)silyl]methyl]-1H-1,2,4-triazole; N-(Triisopropylsilylmethyl)-1,2,4-triazole; TIPS-methyl-1,2,4-triazole; 1-(TIPS-methyl)-1H-1,2,4-triazole; 1,2,4-Triazole, 1-[(triisopropylsilyl)methyl]-; 1-[(Triisopropylsilyl)methyl]-1,2,4-triazole
EINECS	Contact for details

Quality Control

Our 1H-1,2,4-Triazole,1-[[Tris(1-Methylethyl)Silyl]Methyl]-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay purity and impurity profiles. Our quality system is designed to meet the stringent requirements of R&D and scale-up manufacturing across global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid or liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.