Description

Ethyl 4-Chloro-5-Methylthieno[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex APIs, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and specialty polymers due to its conjugated system.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and fine chemicals.

Basic Information

Product Name	Ethyl 4-Chloro-5-Methylthieno[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	101667-98-5
Molecular Formula	C10H9ClN2O2S
Molecular Weight	256.71 g/mol
Synonyms	Ethyl 4-chloro-5-methylthieno[2,3-d]pyrimidine-6-carboxylate; 4-Chloro-5-methylthieno[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; 101667-98-5; Thieno[2,3-d]pyrimidine-6-carboxylic acid, 4-chloro-5-methyl-, ethyl ester; Ethyl 4-chloro-5-methylthieno[2,3-d]pyrimidine-6-carboxylate; 4-Chloro-5-methyl-6-(ethoxycarbonyl)thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-Chloro-5-Methylthieno[2,3-D]Pyrimidine-6-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is released with a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.