Description

1-(3-Indolylmethyl)Nipecotic Acid Ethyl Ester is a specialized organic compound belonging to the class of nipecotic acid derivatives, which are of significant interest in medicinal chemistry and neuroscience research. This compound serves as a valuable synthetic intermediate or building block for the development of novel pharmaceutical agents, particularly those targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of bioactive molecules and potential drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel GABA (γ-aminobutyric acid) uptake inhibitors and related neuroactive compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents for neurological disorders.
• Biochemical Tool Compound: Employed in neuroscience research to study neurotransmitter transport mechanisms and receptor interactions.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, functionalized heterocyclic compounds.
• Contract Research & Development (CRO): Supplied to organizations conducting custom synthesis and process development for client projects.

Basic Information

Product Name	1-(3-Indolylmethyl)Nipecotic Acid Ethyl Ester
CAS No.	101602-77-1
Molecular Formula	C17H22N2O2
Molecular Weight	286.37 g/mol
Synonyms	Ethyl 1-(1H-indol-3-ylmethyl)piperidine-3-carboxylate; 1-[(1H-Indol-3-yl)methyl]-3-piperidinecarboxylic Acid Ethyl Ester; Nipecotic Acid Ethyl Ester, 1-(3-Indolylmethyl) Derivative; 1-(Indol-3-ylmethyl)nipecotic Acid Ethyl Ester; 3-Carbethoxy-1-(indol-3-ylmethyl)piperidine
EINECS	Contact for details

Quality Control

Our production of 1-(3-Indolylmethyl)Nipecotic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.