Description

1,3-Diethyl Ester 2-[3-[(3As,4S,6Ar)-Hexahydro-2-Oxo-1,3-Bis(Phenylmethyl)-1H-Thieno[3,4-D]Imidazol-4-Yl]Propyl] Propanedioic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the production of novel therapeutic agents and as a key building block in complex organic syntheses.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used in drug discovery and lead optimization processes for creating libraries of compounds with potential therapeutic activity.
• Bioconjugation & Probe Development: Serves as a precursor for developing chemical probes and diagnostic agents due to its functionalizable ester and imidazolidinone groups.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a sophisticated, chiral molecular scaffold.
• Academic & Industrial R&D: Utilized in research institutions and corporate R&D departments for developing new synthetic methodologies and exploring structure-activity relationships (SAR).

Basic Information

Product Name	1,3-Diethyl Ester 2-[3-[(3As,4S,6Ar)-Hexahydro-2-Oxo-1,3-Bis(Phenylmethyl)-1H-Thieno[3,4-D]Imidazol-4-Yl]Propyl] Propanedioic Acid
CAS No.	101469-35-6
Molecular Formula	C29H34N2O5S
Molecular Weight	522.66 g/mol
Synonyms	Diethyl 2-[3-[(3aS,4S,6aR)-Hexahydro-2-oxo-1,3-bis(phenylmethyl)-1H-thieno[3,4-d]imidazol-4-yl]propyl]propanedioate; 1,3-Diethyl 2-[3-[(3aS,4S,6aR)-Hexahydro-2-oxo-1,3-bis(phenylmethyl)-1H-thieno[3,4-d]imidazol-4-yl]propyl]malonate; Biotin-PEG3-malonate diethyl ester analog; (3aS,4S,6aR)-Hexahydro-2-oxo-1,3-bis(phenylmethyl)-1H-thieno[3,4-d]imidazole-4-butanoic acid, 4-(diethoxycarbonylmethyl)-; A biotin derivative with a malonate linker.
EINECS	Contact for details

Quality Control

Our 1,3-Diethyl Ester 2-[3-[(3As,4S,6Ar)-Hexahydro-2-Oxo-1,3-Bis(Phenylmethyl)-1H-Thieno[3,4-D]Imidazol-4-Yl]Propyl] Propanedioic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.