Description

2-(4-Fluorophenyl)-3-Methylpyridine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring both a fluorinated aromatic ring and a methyl-substituted pyridine, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl and pyridine motifs.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations.
• Material Science Research: Employed in the creation of organic electronic materials, including charge-transport layers and light-emitting components for OLEDs.
• Chemical Biology Probes: Acts as a scaffold for developing fluorescent tags and molecular probes used in biochemical assays and diagnostic research.

Basic Information

Product Name	2-(4-Fluorophenyl)-3-Methylpyridine
CAS No.	101419-76-5
Molecular Formula	C12H10FN
Molecular Weight	187.21 g/mol
Synonyms	3-Methyl-2-(4-fluorophenyl)pyridine; 2-(p-Fluorophenyl)-3-picoline; 2-(4-Fluorophenyl)-3-picoline; 3-Methyl-2-(4-fluorophenyl)pyridine; 2-(4-Fluorophenyl)-3-methylpyridine; 4-Fluoro-2-(3-pyridyl)benzene (tautomeric form); 101419-76-5
EINECS	Contact for details

Quality Control

Our production of 2-(4-Fluorophenyl)-3-Methylpyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.