Description

5,8,11-Trioxa-2-Azatridecanoic,13-Amino,1,1-Dimethylethyl Ester is a specialized amino-protected polyether derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in providing a protected amine functionality within a flexible, hydrophilic polyether chain, enabling precise molecular design. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel drug candidates, peptide mimetics, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex active pharmaceutical ingredients (APIs), especially those requiring hydrophilic linkers or spacers.
• Peptidomimetics & Conjugates: Used to create peptide-like structures and bioconjugates, enhancing solubility and bioavailability of therapeutic molecules.
• Polymer & Material Science: Serves as a functional monomer or cross-linker for synthesizing specialty polymers, hydrogels, and smart materials with tailored properties.
• Ligand & Catalyst Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal chelation applications.
• Surface Modification: Used to functionalize surfaces and nanoparticles, introducing amine groups for further bioconjugation or chemical attachment.
• Research & Development: A valuable tool in medicinal chemistry and chemical biology for exploring new molecular entities and structure-activity relationships.

Basic Information

Product Name	5,8,11-Trioxa-2-Azatridecanoic,13-Amino,1,1-Dimethylethyl Ester
CAS No.	101187-40-0
Molecular Formula	C15H31NO6
Molecular Weight	321.41 g/mol
Synonyms	tert-Butyl 13-amino-5,8,11-trioxa-2-azatridecanoate; 2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl (tert-butoxycarbonyl)glycinate; Boc-NH-PEG3-CH2CH2COOH tert-butyl ester; Amino-PEG3-Boc acid tert-butyl ester; Fmoc-8-amino-3,6-dioxaoctanoic acid tert-butyl ester (related); BOC-Amino-PEG3-acid t-butyl ester; 13-Amino-5,8,11-trioxa-2-azatridecanoic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 5,8,11-Trioxa-2-Azatridecanoic,13-Amino,1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.