Description

4'-[[Bis(2-Chloroethyl)Amino]Methyl]Benzanilide is a specialized nitrogen mustard derivative with significant potential in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate for creating novel targeted therapeutic agents, particularly in oncology. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of anticancer drugs, antibody-drug conjugates (ADCs), and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel chemotherapeutic agents and targeted cancer therapies.
• Antibody-Drug Conjugate (ADC) Payload Synthesis: Serves as a precursor for cytotoxic warheads designed for targeted drug delivery systems.
• Biochemical Research: Used in academic and industrial laboratories to study alkylating agent mechanisms and structure-activity relationships (SAR).
• Prodrug Development: Employed in the design and synthesis of prodrugs that require specific activation within the body.
• Chemical Biology Tool: Utilized as a molecular probe to investigate DNA alkylation and cellular apoptosis pathways.
• Preclinical Candidate Synthesis: Integral component in the medicinal chemistry workflow for generating new drug candidates for biological evaluation.

Basic Information

Product Name	4'-[[Bis(2-Chloroethyl)Amino]Methyl]Benzanilide
CAS No.	100678-35-1
Molecular Formula	C19H22Cl2N2O
Molecular Weight	365.30 g/mol
Synonyms	N-[4-[[Bis(2-chloroethyl)amino]methyl]phenyl]benzamide; Benzamide, N-[4-[[bis(2-chloroethyl)amino]methyl]phenyl]-; 4'-[Bis(2-chloroethyl)aminomethyl]benzanilide; Mustard Benzanilide Derivative; Nitrogen Mustard Benzanilide; ADC Linker-Payload Intermediate; Chlorambucil Benzanilide Analog
EINECS	Contact for details

Quality Control

Our 4'-[[Bis(2-Chloroethyl)Amino]Methyl]Benzanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.