Description

Acetic Acid 2-Trimethylsilanylmethyl-Benzyl Ester is a specialized organosilicon ester compound, identified by CAS NO 100642-59-9. This chemical serves as a valuable silyl-protecting group precursor and a versatile synthetic intermediate in advanced organic synthesis. It is primarily required by pharmaceutical R&D and fine chemical manufacturing sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing functional groups.
• Peptide Synthesis: Used as a reagent for the protection of hydroxyl or carboxyl groups during solid-phase and solution-phase peptide synthesis.
• Organometallic Chemistry: Acts as a precursor for generating organosilicon reagents used in cross-coupling reactions and catalysis.
• Material Science Research: Employed in the development of novel silicone-based polymers and hybrid organic-inorganic materials.
• Agrochemical Synthesis: Intermediate in the production of advanced, silicon-enhanced crop protection agents.
• Academic & Industrial R&D: A critical tool for chemists in exploratory research for new synthetic methodologies.

Basic Information

Product Name	Acetic Acid 2-Trimethylsilanylmethyl-Benzyl Ester
CAS No.	100642-59-9
Molecular Formula	C13H20O2Si
Molecular Weight	236.38 g/mol
Synonyms	2-[(Trimethylsilyl)methyl]benzyl acetate; Benzyl alcohol, 2-[(trimethylsilyl)methyl]-, acetate; Acetic acid, [2-[(trimethylsilyl)methyl]phenyl]methyl ester; (2-((Trimethylsilyl)methyl)phenyl)methyl acetate; TMSM-Benzyl Acetate; Silicon-protected benzyl acetate derivative; 2-(Trimethylsilylmethyl)benzyl acetate
EINECS	Contact for details

Quality Control

Our production of Acetic Acid 2-Trimethylsilanylmethyl-Benzyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including GC, HPLC, and NMR to confirm identity and quantify impurities. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.