Description

3-(2-Isocyanoethyl)-1H-Indole is a versatile and highly reactive indole derivative containing a strategically positioned isocyano functional group. This compound serves as a critical advanced pharmaceutical intermediate (API) and a valuable building block in organic synthesis, enabling the construction of complex heterocyclic frameworks. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing new pesticides and herbicides with novel modes of action.
• Organic Synthesis: Valuable reagent for multicomponent reactions (MCRs) and the construction of indole-fused heterocycles.
• Material Science: Potential monomer or functionalizing agent for specialty polymers and advanced materials.
• Chemical Biology: Used in probe and linker development for studying biological systems due to its reactive isocyanide group.

Basic Information

Product Name	3-(2-Isocyanoethyl)-1H-Indole
CAS No.	100571-64-0
Molecular Formula	C11H10N2
Molecular Weight	170.21 g/mol
Synonyms	1H-Indole-3-ethanenitrile, 2-isocyano-; 3-(2-Isocyanatoethyl)indole; 2-(1H-Indol-3-yl)ethyl isocyanide; 3-(2-Isocyanoethyl)indole; 2-(3-Indolyl)ethyl isocyanide
EINECS	Contact for details

Quality Control

Our 3-(2-Isocyanoethyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.