Description

Benzoyl Chloride, 2-(Trimethylsilyl)- (9Ci) is a specialized organosilicon reagent that combines the reactivity of a benzoyl chloride with the protective and modifying properties of a trimethylsilyl group. This compound is a valuable synthetic intermediate, enabling precise chemical transformations in advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing protected or modified benzoyl moieties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the silyl group aids in selective reactions.
• Silicon-Containing Polymer Research: Serves as a monomer or cross-linking agent in the development of specialty silicones and hybrid organic-inorganic polymers.
• Advanced Material Precursor: Employed in the fabrication of functionalized surfaces, coatings, and nanomaterials requiring specific silicon-based anchoring groups.
• Organic Synthesis Reagent: Facilitates acylation reactions where the ortho-trimethylsilyl group provides steric and electronic control, directing regioselectivity.
• Protecting Group Strategy: The trimethylsilyl group can act as a temporary protecting group for hydroxyl or other sensitive functionalities during multi-step syntheses.

Basic Information

Item	Detail
Product Name	Benzoyl Chloride, 2-(Trimethylsilyl)- (9Ci)
CAS No.	100475-98-7
Molecular Formula	C10H13ClOSi
Molecular Weight	212.75 g/mol
Synonyms	2-(Trimethylsilyl)benzoyl chloride; o-(Trimethylsilyl)benzoyl chloride; Benzoyl chloride, o-(trimethylsilyl)-; 2-Trimethylsilylbenzoyl chloride; (2-Trimethylsilylphenyl)carbonyl chloride; TMS-Benzoyl Chloride; 2-TMS-Benzoyl Chloride
EINECS	Contact for details

Quality Control

Our production of Benzoyl Chloride, 2-(Trimethylsilyl)- (9Ci) adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot is characterized by modern analytical techniques including NMR, GC, and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.