Description

Diethyl (6-Bromohexanyl)Phosphonate is a high-purity organophosphorus compound widely utilized as a key synthetic intermediate. Its value lies in its bifunctional reactivity, featuring both a phosphonate ester group and a terminal bromoalkyl chain, enabling its use in carbon-carbon bond-forming reactions and as a versatile linker in organic synthesis. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a phosphonate or extended alkyl chain moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that incorporate phosphonate functionalities.
• Material Science: Serves as a precursor for flame retardants, plasticizers, and specialty polymers where phosphonate groups enhance material properties.
• Organic Synthesis Reagent: Employed in Horner-Wadsworth-Emmons (HWE) olefination reactions to generate alkenes, a fundamental transformation in complex molecule assembly.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel phosphonate-based ligands used in coordination chemistry and catalysis.
• Bioconjugation and Linker Chemistry: The reactive bromo group allows for its use as a heterobifunctional linker in bioconjugation and prodrug strategies.

Basic Information

Item	Detail
Product Name	Diethyl (6-Bromohexanyl)Phosphonate
CAS No.	100462-72-4
Molecular Formula	C10H22BrO3P
Molecular Weight	301.16 g/mol
Synonyms	Diethyl (6-Bromohexyl)phosphonate; (6-Bromohexyl)phosphonic Acid Diethyl Ester; Diethyl 6-Bromohexylphosphonate; 6-Bromohexylphosphonic Acid Diethyl Ester; Diethyl Phosphorobromidate Hexyl Ester (related); BR-HEX-P(O)(OEt)2; (Bromohexyl)diethoxyphosphine Oxide
EINECS	Contact for details

Quality Control

Every batch of Diethyl (6-Bromohexanyl)Phosphonate is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure high purity and consistency that meets the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.25 g/cm³
Refractive Index (n20D)	~1.470

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.