Description

Benzyl [1-Cyano-1-Methylethyl]Carbamate is a specialized carbamate derivative featuring a cyano-isopropyl moiety, serving as a versatile and valuable building block in advanced organic synthesis. Its primary commercial value lies in its role as a key protected intermediate for the preparation of amino acids, peptides, and other nitrogen-containing bioactive molecules. This compound is particularly essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, reliable intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other peptide-based therapeutics.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid precursor, enabling the controlled assembly of complex peptide sequences.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced herbicides, fungicides, and insecticides that require specific carbamate or amino acid motifs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, chiral auxiliaries, and custom-designed molecular scaffolds for research and commercial applications.
• Material Science Research: Investigated as a monomer or modifying agent for the synthesis of functional polymers with tailored properties.

Basic Information

Product Name	Benzyl [1-Cyano-1-Methylethyl]Carbamate
CAS No.	100134-82-5
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	Benzyl (1-cyano-1-methylethyl)carbamate; Carbamic acid, N-(1-cyano-1-methylethyl)-, phenylmethyl ester; 2-Cyano-2-propylcarbamic acid benzyl ester; Benzyl 2-cyano-2-propylcarbamate; (1-Cyano-1-methylethyl)carbamic acid benzyl ester; Z-Aib(CN)-OH benzyl ester (common peptide chemistry abbreviation); Bzl-Aib(CN)-OH
EINECS	Contact for details

Quality Control

Our Benzyl [1-Cyano-1-Methylethyl]Carbamate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to verify identity and purity. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP and ISO 9001 compliant manufacturing practices to meet the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.