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3',4'-Dihydro-Spiro[Cyclohexane-1,1'(2'H)-Pyrido[3,4-B]Indole]-3'-Carboxylic Acid CAS NO 100068-46-0


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CAS No.:100068-46-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3',4'-Dihydro-Spiro[Cyclohexane-1,1'(2'H)-Pyrido[3,4-B]Indole]-3'-Carboxylic Acid is a high-purity, complex heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the research and development of novel pharmaceutical agents, particularly those targeting central nervous system disorders. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing sophisticated molecular architectures.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
  • Organic Synthesis Building Block: Employed in the construction of complex spirocyclic and polycyclic alkaloid-like frameworks.
  • Process Chemistry Development: Serves as a key material for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
  • Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.
  • Biochemical Research: Investigated for its biological activity and potential as a tool compound in biochemical assays.

Basic Information

Product Name 3',4'-Dihydro-Spiro[Cyclohexane-1,1'(2'H)-Pyrido[3,4-B]Indole]-3'-Carboxylic Acid
CAS No. 100068-46-0
Molecular Formula C17H20N2O2
Molecular Weight 284.36 g/mol
Synonyms Spiro[cyclohexane-1,1'(2'H)-pyrido[3,4-b]indole]-3'-carboxylic acid, 3',4'-dihydro-; 3',4'-Dihydro-1'H-spiro[cyclohexane-1,2'-pyrido[3,4-b]indole]-3'-carboxylic acid; 100068-46-0; Spirocyclic pyridoindole carboxylic acid; 1'H-Spiro[cyclohexane-1,2'-pyrido[3,4-b]indole]-3'-carboxylic acid, 3',4'-dihydro-; Dihydrospiropyridoindole-3'-carboxylic acid
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Quality Control

Our 3',4'-Dihydro-Spiro[Cyclohexane-1,1'(2'H)-Pyrido[3,4-B]Indole]-3'-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure compliance with stringent specifications suitable for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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