Description

(2R,6R)-2-tert-Butyl-6-Methyl-1,3-Dioxan-4-One CAS NO 100017-18-3 is a chiral 1,3-dioxan-4-one derivative, a valuable building block in asymmetric synthesis. Its defined stereochemistry and reactive carbonyl group make it a critical intermediate for constructing complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, including potential antiviral and central nervous system (CNS) agents.
• Asymmetric Catalysis: Serves as a precursor for novel chiral auxiliaries, catalysts, and ligands used in stereoselective transformations.
• Fine Chemical Synthesis: Building block for creating complex natural product analogs and specialty chemicals requiring specific stereocenters.
• Academic & Industrial R&D: Used in method development for new asymmetric synthesis routes and studying reaction mechanisms.
• Agrochemical Research: Intermediate in the development of chiral active ingredients for crop protection products.

Basic Information

Product Name	(2R,6R)-2-tert-Butyl-6-Methyl-1,3-Dioxan-4-One
CAS No.	100017-18-3
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(2R,6R)-2-(1,1-Dimethylethyl)-6-methyl-1,3-dioxan-4-one; (2R,6R)-2-tert-Butyl-6-methyl-1,3-dioxan-4-one; (R,R)-2-tert-Butyl-6-methyl-1,3-dioxan-4-one; (2R,6R)-2-tert-Butyl-6-methyl-m-dioxan-4-one; 1,3-Dioxan-4-one, 2-(1,1-dimethylethyl)-6-methyl-, (2R,6R)-; Chiral Dioxanone Derivative; tert-Butyl Methyl Dioxanone (stereospecific)
EINECS	Contact for details

Quality Control

Our (2R,6R)-2-tert-Butyl-6-Methyl-1,3-Dioxan-4-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.