Description

Norethindrone Sulfate CAS NO 19778-24-6 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) derived from the progestin norethindrone. This compound is critical for ensuring the efficacy and stability of final hormonal formulations. It is primarily required by pharmaceutical manufacturers and research institutions developing contraceptive and hormone replacement therapies.

Application

• Pharmaceutical API Synthesis: A key intermediate in the production of finished dosage forms of norethindrone-based medications.
• Oral Contraceptives: Used in the formulation of combination and progestin-only birth control pills.
• Hormone Replacement Therapy (HRT): A component in treatments for managing menopausal symptoms and hormonal imbalances.
• Gynecological Therapeutics: Employed in medications for endometriosis, abnormal uterine bleeding, and other related conditions.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in laboratories.
• Research & Development: Utilized in preclinical and clinical studies for developing new hormonal agents and delivery systems.

Basic Information

Product Name	Norethindrone Sulfate
CAS No.	19778-24-6
Molecular Formula	C₂₀H₂₆O₅S
Molecular Weight	378.48 g/mol
Synonyms	Norethisterone Sulfate; 17α-Ethynyl-19-nortestosterone Sulfate; 19-Nor-17α-pregn-4-en-20-yn-3-one, 17-(sulfooxy)-, (17α)-; Norpregneninolone Sulfate; NSC 95698; Ethinylestrenolone Sulfate; Norethindrone Hydrogen Sulfate
EINECS	Contact for details

Quality Control

Our Norethindrone Sulfate is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.