Description

3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzamide is a specialized nitrogen mustard derivative with a benzamide core structure, offering a unique combination of alkylating reactivity and molecular scaffold functionality. This compound matters for its role as a critical intermediate in advanced pharmaceutical synthesis and targeted chemical research. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential anticancer agents and other nitrogen mustard-based therapeutics.
• Biochemical Research: Used in the study of alkylating agents and their mechanisms of action on DNA and cellular proteins.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzamide
CAS No.	19768-73-1
Molecular Formula	C₁₃H₁₈Cl₂N₂O
Molecular Weight	289.20 g/mol
Synonyms	4-Methyl-3-[bis(2-chloroethyl)amino]benzamide; NSC 176319; 3-[Bis(2-chloroethyl)amino]-4-methyl-benzamide; Benzamide, 3-[bis(2-chloroethyl)amino]-4-methyl-; 4-Methyl-3-(bis(2-chloroethyl)amino)benzamide; 3-(Bis(2-chloroethyl)amino)-p-toluamide; p-Toluamide, 3-(bis(2-chloroethyl)amino)-
EINECS	Contact for details

Quality Control

Our 3-[Bis(2-Chloroethyl)Amino]-4-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing the results are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued light or in amber containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.