Description

Curcumin 4,4'-Diacetate is a chemically modified derivative of curcumin, a natural polyphenol found in turmeric. This acetylated form offers enhanced stability and altered solubility profiles compared to its parent compound, making it a valuable intermediate for advanced research and synthesis. It is primarily utilized in the pharmaceutical, nutraceutical, and life science research sectors for developing novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel curcumin analogs with potential anti-inflammatory, anticancer, and neuroprotective properties.
• Biochemical Research: Used as a stable probe or standard in studying bioavailability, metabolism, and the structure-activity relationships (SAR) of curcuminoids.
• Nutraceutical Development: Investigated for use in formulating stabilized dietary supplements with targeted release profiles.
• Cosmetic Ingredient Precursor: Serves as a synthetic intermediate for developing stable, skin-beneficial actives in anti-aging and brightening formulations.
• Organic Synthesis Building Block: Employed in academic and industrial organic chemistry for creating complex molecular libraries.
• Analytical Reference Standard: Provides a high-purity standard for quality control and analytical method development (HPLC, LC-MS) in related product manufacturing.

Basic Information

Product Name	Curcumin 4,4'-Diacetate
CAS No.	19697-86-0
Molecular Formula	C25H24O8
Molecular Weight	452.45 g/mol
Synonyms	Diacetylcurcumin; Curcumin Diacetate; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione Diacetate; Turmeric Yellow Diacetate; (1E,6E)-1,7-Bis(4-acetoxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; HCA (Hexahydrocurcumin Acetate precursor); Curcuminoid Derivative
EINECS	Contact for details

Quality Control

Our Curcumin 4,4'-Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.