Description

Diethyl 4-Chlorophenyl Malonate is a versatile organic ester building block, primarily valued for its role as a key intermediate in the synthesis of complex molecules. Its structure, featuring both a malonate ester and a chlorophenyl group, makes it a critical precursor in pharmaceutical and agrochemical research and development. This compound is essential for manufacturers and R&D laboratories engaged in creating active pharmaceutical ingredients (APIs), fine chemicals, and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing arylacetic acid or heterocyclic frameworks.
• Agrochemical Synthesis: Serves as a key precursor in the development of herbicides, fungicides, and insecticides, leveraging the reactivity of the malonate moiety.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and functional materials requiring specific aryl-substituted malonate structures.
• Research & Development: Employed in organic synthesis laboratories for method development, scale-up studies, and the creation of novel chemical entities.
• Chemical Synthesis: Utilized in Knoevenagel condensations, Michael additions, and other carbon-carbon bond-forming reactions to construct complex molecular architectures.

Basic Information

Product Name	Diethyl 4-Chlorophenyl Malonate
CAS No.	19677-37-3
Molecular Formula	C13H15ClO4
Molecular Weight	270.71 g/mol
Synonyms	Diethyl (4-chlorophenyl)malonate; 4-Chlorophenylmalonic Acid Diethyl Ester; Propanedioic acid, 2-(4-chlorophenyl)-, diethyl ester; Diethyl p-chlorophenylmalonate; (4-Chlorophenyl)malonic Acid Diethyl Ester; Ethyl 4-chlorophenylmalonate; Diethyl 4-chlorobenzylmalonate (common misnomer); NSC 404087
EINECS	Contact for details

Quality Control

Our Diethyl 4-Chlorophenyl Malonate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.