Description

8-Isopropylidene-1,4-Dioxa-Spiro[4.5]Decane is a specialized spirocyclic ketal compound with the CAS number 19620-35-0. This versatile chemical intermediate is valued for its unique bicyclic structure, which provides a rigid framework and protective functionality for carbonyl groups in complex organic syntheses. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fragrance sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, particularly those requiring spirocyclic or protected ketone motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its structure can contribute to biological activity and stability.
• Fragrance & Flavor Chemistry: Acts as a precursor or stabilizing agent for certain aroma chemicals and flavor compounds.
• Organic Synthesis Reagent: Employed as a protecting group for ketones and aldehydes in multi-step synthetic routes, enabling selective reactions.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for chemists exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	8-Isopropylidene-1,4-Dioxa-Spiro[4.5]Decane
CAS No.	19620-35-0
Molecular Formula	C11H18O2
Molecular Weight	182.26 g/mol
Synonyms	1,4-Dioxaspiro[4.5]decane, 8-isopropylidene-; 8-Isopropylidene-1,4-dioxaspiro[4.5]decane; Cyclohexanone, 2,2-dimethyl-, ethylene ketal; 2,2-Dimethylcyclohexanone ethylene ketal; Spiro[1,3-dioxolane-2,1'-cyclohexane], 4,4-dimethyl-; Acetaldehyde, cyclohexylidene-, cyclic ethylene acetal; Contact for additional synonyms.
EINECS	243-197-9

Quality Control

Our 8-Isopropylidene-1,4-Dioxa-Spiro[4.5]Decane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.460 - 1.470
Density (g/mL, 20°C)	0.98 - 1.02

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.