Description

(1R,20'S)-20'-Dimethylamino-2-Methylspiro[1H-Isoindole-1,3'-[5α]Pregnan]-3(2H)-One is a complex, high-purity steroidal alkaloid derivative with a unique spirocyclic structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a sophisticated synthetic intermediate or a potential pharmacophore. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel steroid-based therapeutics, neuroactive agents, and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel steroid-derived drug candidates.
• Medicinal Chemistry Research: Used as a reference standard or a starting material in structure-activity relationship (SAR) studies for central nervous system (CNS) targets.
• Biochemical Tool Compound: Employed in preclinical research to investigate interactions with specific steroid hormone receptors or neural pathways.
• Advanced Organic Synthesis: Utilized in academic and industrial R&D for developing new synthetic methodologies involving complex alkaloid and steroid frameworks.
• Reference Standard for Analytical Labs: Provides a high-purity standard for method development and quality control in analytical testing laboratories.

Basic Information

Item	Details
Product Name	(1R,20'S)-20'-Dimethylamino-2-Methylspiro[1H-Isoindole-1,3'-[5α]Pregnan]-3(2H)-One
CAS No.	19587-41-8
Molecular Formula	C31H44N2O
Molecular Weight	460.70 g/mol
Synonyms	20'-Dimethylamino-2-methylspiro[1H-isoindole-1,3'-[5α]pregnan]-3(2H)-one; 2-Methyl-20'-dimethylaminospiro[1H-isoindole-1,3'-[5α]pregnan]-3(2H)-one; Spiro[1H-isoindole-1,3'-[5α]pregnan]-3(2H)-one, 20'-dimethylamino-2-methyl-; (1R,20'S)-20'-Dimethylamino-2-methylspiro[1H-isoindole-1,3'-[5α]pregnan]-3(2H)-one; 19587-41-8; A steroidal spiroisoindole alkaloid derivative.
EINECS	Contact for details

Quality Control

Our (1R,20'S)-20'-Dimethylamino-2-Methylspiro[1H-Isoindole-1,3'-[5α]Pregnan]-3(2H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.