Description

o-Benzyl-L-Serine Methyl Ester Hydrochloride is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. This compound is essential for the controlled introduction of the serine moiety into complex molecular architectures, particularly in peptide chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers in the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and other fine chemicals.

Application

• Peptide Synthesis: A crucial intermediate for the solid-phase and solution-phase synthesis of peptides, protecting the serine side chain during coupling reactions.
• Pharmaceutical Intermediates: Serves as a chiral synthon in the research and production of novel drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation & Linker Chemistry: Used in the preparation of modified peptides and protein conjugates for drug delivery systems and diagnostic applications.
• Chemical Biology Research: Employed in the synthesis of peptide mimetics, enzyme inhibitors, and probes for studying biological mechanisms.
• Fine Chemical Production: Acts as a building block for the manufacture of complex organic molecules requiring specific stereochemistry.

Basic Information

Product Name	o-Benzyl-L-Serine Methyl Ester Hydrochloride
CAS No.	19525-87-2
Molecular Formula	C11H16ClNO3
Molecular Weight	245.70 g/mol
Synonyms	L-Serine, O-benzyl-, methyl ester, hydrochloride; Methyl O-benzyl-L-serinate hydrochloride; (S)-Methyl 2-amino-3-(benzyloxy)propanoate hydrochloride; H-Ser(Bzl)-OMe·HCl; Benzyl L-serinate methyl ester hydrochloride; O-Benzylserine methyl ester HCl; Methyl (S)-3-(benzyloxy)-2-aminopropanoate hydrochloride
EINECS	Contact for details

Quality Control

Our o-Benzyl-L-Serine Methyl Ester Hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.