Description

4-Bromopyridine Hydrochloride is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the bromine atom offers a site for cross-coupling reactions and the pyridine ring acts as a directing group or a basic nitrogen source. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, leveraging the pyridine scaffold for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing complex ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as conductive polymers and molecular sensors.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
• Cross-Coupling Reactions: Acts as a reliable substrate in Suzuki, Stille, and Negishi couplings to form biaryl and other complex structures.

Basic Information

Product Name	4-Bromopyridine Hydrochloride
CAS No.	19524-06-2
Molecular Formula	C5H5BrN·HCl
Molecular Weight	192.46 g/mol (Free base: 157.99 g/mol)
Synonyms	4-Bromopyridine HCl; 4-Bromopyridine Hydrochloride Salt; Pyridine, 4-bromo-, hydrochloride; 4-BrPy·HCl; 4-Bromopyridinium Chloride; 4-Pyridyl Bromide Hydrochloride; 4-Bromopyridine Monohydrochloride
EINECS	Contact for details

Quality Control

Our 4-Bromopyridine Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.