Description

n-[n-[n-(Heptafluorobutyryl)Glycyl]Glycyl]Glycine Methyl Ester is a specialized fluorinated peptide derivative, serving as a critical building block and analytical standard in advanced chemical synthesis. This compound matters for its role in introducing the heptafluorobutyryl (HFB) moiety, a powerful tool for enhancing detection sensitivity and volatility in analytical applications. It is primarily needed by researchers and manufacturers in the pharmaceutical, proteomics, and analytical chemistry sectors for developing novel compounds and high-sensitivity detection methods.

Application

• Derivatization Agent in GC/MS and LC/MS: Used to derivative amino acids, peptides, and amines to improve their volatility, thermal stability, and detection sensitivity for trace analysis.
• Biochemical Research & Proteomics: Serves as a key synthetic intermediate or tagging reagent in the study of peptide structure, function, and post-translational modifications.
• Pharmaceutical Intermediate: Employed in the synthesis of complex fluorinated peptide-based drug candidates and diagnostic agents.
• Reference Standard: Used as a high-purity calibration standard in analytical laboratories for method development and quality control.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and biological pathways.

Basic Information

Product Name	n-[n-[n-(Heptafluorobutyryl)Glycyl]Glycyl]Glycine Methyl Ester
CAS No.	19444-87-2
Molecular Formula	C12H12F7N3O5
Molecular Weight	411.23 g/mol
Synonyms	N-(N-(N-(Heptafluorobutyryl)glycyl)glycyl)glycine methyl ester; HFB-Gly-Gly-Gly-OMe; Methyl N-[N-[N-(2,2,3,3,4,4,4-heptafluorobutanoyl)glycyl]glycyl]glycinate; Glycine, N-[N-[N-(heptafluorobutyryl)glycyl]glycyl]-, methyl ester; Heptafluorobutyryl-triglycine methyl ester; F7C3CO-Gly-Gly-Gly-OMe; 19444-87-2; Methyl triglycine heptafluorobutyrate
EINECS	Contact for details

Quality Control

Our n-[n-[n-(Heptafluorobutyryl)Glycyl]Glycyl]Glycine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.