Description

4-Nitrophenyl Bromoacetate is a high-purity, light-sensitive organic ester compound, serving as a critical building block and reagent in advanced chemical synthesis. Its primary value lies in its bifunctional reactivity, featuring both an activated ester group and a halogenated moiety, which makes it indispensable for selective coupling and derivatization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), especially for creating ester and amide linkages.
• Peptide Synthesis: Used as an activating agent or protecting group reagent in solid-phase and solution-phase peptide chemistry.
• Bioconjugation: Facilitates the labeling and cross-linking of biomolecules (proteins, antibodies) for diagnostic and research applications.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Employed as a monomer or modifying agent for synthesizing specialty polymers with specific functional groups.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and mechanism.
• Material Science: Acts as a surface modifier or coupling agent for functionalizing nanomaterials and other advanced materials.

Basic Information

Product Name	4-Nitrophenyl Bromoacetate
CAS No.	19199-82-7
Molecular Formula	C8H6BrNO4
Molecular Weight	260.04 g/mol
Synonyms	p-Nitrophenyl Bromoacetate; Bromoacetic Acid 4-Nitrophenyl Ester; (4-Nitrophenoxy)carbonylmethyl Bromide; 4-Nitrophenyl 2-Bromoacetate; 2-Bromoacetic Acid 4-Nitrophenyl Ester; Bromoacetyl p-Nitrophenyl Ester; p-Nitrophenyl 2-Bromoacetate; NSC 401106
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl Bromoacetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of research and production applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents. The container must be kept tightly sealed due to the compound's sensitivity to moisture and potential volatility.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.