Description

Desoxypodophyllotoxin is a potent aryltetralin lignan derivative and a key intermediate in the synthesis of various biologically active compounds. Its structural framework is crucial for developing pharmaceutical agents, particularly in oncology and antiviral research. This high-purity compound is essential for research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in advanced synthetic chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor for the semi-synthesis of chemotherapeutic agents like etoposide and teniposide.
• Anticancer Research: Used as a reference standard and active compound in studies targeting tubulin polymerization inhibition and apoptosis induction.
• Antiviral Agent Development: Investigated for its potential activity against various viral pathogens in preclinical research settings.
• Biochemical Tool Compound: Employed in cell biology and pharmacology to study cell cycle arrest and mechanisms of cytotoxicity.
• Natural Product Synthesis: A fundamental building block for the total synthesis of complex podophyllotoxin-related lignans.
• Reference Standard: Used in analytical laboratories for quality control and method development via HPLC or LC-MS.

Basic Information

Product Name	Desoxypodophyllotoxin
CAS No.	19186-35-7
Molecular Formula	C22H22O7
Molecular Weight	398.41 g/mol
Synonyms	Desoxy podophyllotoxin; (-)-Desoxypodophyllotoxin; Anthricin; NSC 33410; 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one; Deoxypodophyllotoxin; 4'-Demethyldeoxypodophyllotoxin (context-dependent)
EINECS	Contact for details

Quality Control

Our Desoxypodophyllotoxin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.