Description

2-[3-[5,6-Dichloro-1-Ethyl-1,3-Dihydro-3-(3-Sulphonatopropyl)-2H-Benzimidazol-2-Ylidene]Prop-1-Enyl]-3-Ethylbenzoxazolium is a high-purity, sulfonated cyanine dye intermediate of significant commercial and research importance. Its value lies in its role as a key precursor for synthesizing near-infrared (NIR) fluorescent probes and labels, which are critical for advanced biomedical imaging and diagnostic applications. This compound is essential for manufacturers and R&D laboratories in the life sciences, analytical chemistry, and specialty chemical sectors seeking to develop sensitive detection systems.

Application

• Synthesis of NIR Fluorescent Dyes & Probes: Primary use as a building block for creating cyanine dyes with absorption and emission in the near-infrared region, enabling deeper tissue imaging with minimal background interference.
• Bioconjugation & Labeling Reagents: Used to produce reactive derivatives (e.g., NHS esters, maleimides) for labeling proteins, antibodies, nucleic acids, and other biomolecules for fluorescence-based assays.
• Bioimaging & Diagnostics: Integral in the development of contrast agents and probes for in vivo and in vitro imaging, flow cytometry, and immunohistochemistry.
• Photodynamic Therapy (PDT) Research: Serves as a starting material for photosensitizers used in investigational cancer and antimicrobial therapies.
• Material Science & Sensors: Applied in the fabrication of advanced polymeric materials and chemical sensors that utilize optical properties for detection.
• Analytical Chemistry Standards: Used as a reference standard or calibrant in chromatographic (HPLC) and spectroscopic methods for quality control of related dye products.

Basic Information

Item	Details
Product Name	2-[3-[5,6-Dichloro-1-Ethyl-1,3-Dihydro-3-(3-Sulphonatopropyl)-2H-Benzimidazol-2-Ylidene]Prop-1-Enyl]-3-Ethylbenzoxazolium
CAS No.	19163-98-5
Molecular Formula	C25H28Cl2N3O4S
Molecular Weight	537.47 g/mol
Synonyms	IR-783 Sulphonated Precursor; 2-[3-[5,6-Dichloro-1-ethyl-1,3-dihydro-3-(3-sulfonatopropyl)-2H-benzimidazol-2-ylidene]-1-propenyl]-3-ethylbenzoxazolium; 3-Ethyl-2-[3-(1,3,3-trimethyl-5-sulfonatoindolin-2-ylidene)propenyl]benzoxazolium derivative; Cyanine dye intermediate, sulphonated; Benzoxazolium, 2-[3-[5,6-dichloro-1-ethyl-1,3-dihydro-3-(3-sulfonatopropyl)-2H-benzimidazol-2-ylidene]-1-propenyl]-3-ethyl-; NIR dye salt; Sulfo-Cyanine dye building block
EINECS	Contact for details

Quality Control

Every batch of 2-[3-[5,6-Dichloro-1-Ethyl-1,3-Dihydro-3-(3-Sulphonatopropyl)-2H-Benzimidazol-2-Ylidene]Prop-1-Enyl]-3-Ethylbenzoxazolium is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure the material meets the precise requirements for sensitive fluorescence applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	Dark green to blue-black powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.