Description

Trimethylsilylsucrose is a chemically modified derivative of sucrose where hydroxyl groups are protected by trimethylsilyl (TMS) groups. This modification is critical for enhancing the stability and solubility of the sucrose molecule in non-polar environments, facilitating its use in advanced synthetic chemistry. It serves as a valuable intermediate and protecting group reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex carbohydrate-based drugs and prodrugs where selective protection of sugar hydroxyl groups is required.
• Agrochemical Synthesis: Serves as a building block for creating novel, sugar-conjugated pesticides and plant growth regulators.
• Glycochemistry Research: A key reagent for the study and synthesis of oligosaccharides, glycoconjugates, and other complex carbohydrates in academic and industrial R&D.
• Protecting Group Chemistry: Employed to temporarily mask reactive hydroxyl groups on sucrose during multi-step organic synthesis, allowing for selective reactions at other sites.
• Material Science: Potential use in the development of specialty polymers, surfactants, or coatings derived from renewable sugar feedstocks.
• Analytical Standard: Used as a reference standard in chromatographic (e.g., GC, HPLC) and spectroscopic analysis for quality control and method development.

Basic Information

Product Name	Trimethylsilylsucrose
CAS No.	19159-25-2
Molecular Formula	C21H48O11Si4
Molecular Weight	585.9 g/mol
Synonyms	Sucrose, octakis(trimethylsilyl) ether; Octakis-O-(trimethylsilyl)sucrose; Sucrose TMS derivative; Sucrose, per-O-trimethylsilyl; TMS-sucrose; 1,3,4,6-Tetra-O-trimethylsilyl-α-D-glucopyranosyl 2,3,4,6-tetra-O-trimethylsilyl-β-D-fructofuranoside; NSC 406925
EINECS	Contact for details

Quality Control

Our Trimethylsilylsucrose is produced under controlled conditions to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to confirm identity and purity. Certificates of Analysis (COA) documenting all critical quality parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.