Description

2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-6-Deoxy-L-Mannose is a highly functionalized, fully protected carbohydrate derivative, specifically a per-silylated deoxy sugar. This compound is a crucial synthetic intermediate in organic and medicinal chemistry, valued for its role in constructing complex oligosaccharides and nucleoside analogs. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analogs and antiviral/antitumor agents.
• Carbohydrate Chemistry: Essential precursor for the controlled, regioselective synthesis of complex oligosaccharides and glycoconjugates.
• Glycobiology Research: Used in the study of carbohydrate-protein interactions and the development of glycomimetic drugs.
• Process Chemistry: Employed in the scalable production of specialty sugars and chiral synthons under protective group chemistry.
• Fine Chemical Synthesis: Serves as a versatile starting material for creating labeled compounds, diagnostics, and other high-value chemical entities.

Basic Information

Product Name	2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-6-Deoxy-L-Mannose
CAS No.	19127-15-2
Molecular Formula	C22H52O5Si4
Molecular Weight	509.0 g/mol
Synonyms	6-Deoxy-2,3,4,5-tetra-O-(trimethylsilyl)-L-mannose; L-6-Deoxymannose, 2,3,4,5-tetrakis-O-(trimethylsilyl)-; Per-O-trimethylsilyl-6-deoxy-L-mannose; 6-Deoxy-L-mannose tetrakis(trimethylsilyl) ether; Tetrakis-O-(trimethylsilyl)-6-deoxy-L-mannopyranose; Fully protected 6-deoxy-L-mannose; TMS-protected 6-deoxy-L-mannose
EINECS	Contact for details

Quality Control

Our production of 2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-6-Deoxy-L-Mannose adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Quality is verified through advanced analytical techniques including NMR, HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.