Description

2-(p-Tolylaminomethylene)Malonic Acid Diethyl Ester is a versatile malonic acid derivative and a key synthetic intermediate in organic chemistry. Its molecular structure, featuring both an ester and an aminomethylene group, makes it a valuable building block for constructing complex heterocyclic and pharmaceutical compounds. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various heterocyclic compounds, including quinolones, pyridines, and other nitrogen-containing scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging its reactivity to create complex molecular architectures.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and other specialty chemicals requiring specific functional group transformations.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic synthesis, particularly in Knoevenagel condensation and related C-C bond-forming reactions.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or other functional materials.

Basic Information

Product Name	2-(p-Tolylaminomethylene)Malonic Acid Diethyl Ester
CAS No.	19056-84-9
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	Diethyl 2-[(4-methylphenyl)amino]methylene]propanedioate; Diethyl (4-methylphenylamino)methylene malonate; 2-[(4-Methylphenyl)amino]methylene]malonic Acid Diethyl Ester; p-Tolylaminomethylenemalonic Acid Diethyl Ester; Propanedioic acid, 2-[(4-methylphenyl)amino]methylene]-, 1,3-diethyl ester; Ethyl (4-methylphenylimino)malonate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-(p-Tolylaminomethylene)Malonic Acid Diethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, appearance, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.