Description

N1-(2-Hydroxyethyl) Flurazepam Hydrochloride is a key pharmaceutical intermediate and a derivative of the benzodiazepine class. This compound is essential for research and development in medicinal chemistry, particularly for studying the structure-activity relationships of psychoactive substances. It is primarily utilized by pharmaceutical R&D laboratories, analytical reference standard providers, and specialized chemical manufacturers focused on active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of benzodiazepine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Medicinal Chemistry Research: Serves as a precursor or model compound for studying metabolic pathways, pharmacokinetics, and receptor binding affinities.
• Biochemical Research: Employed in in-vitro studies to investigate the mechanisms of action of GABA-A receptor modulators.
• Controlled Substance Analog Research: Used in forensic and regulatory science for the development of analytical detection methods.

Basic Information

Item	Detail
Product Name	N1-(2-Hydroxyethyl) Flurazepam Hydrochloride
CAS No.	19011-77-9
Molecular Formula	C₂₃H₂₅ClFN₃O₃ • HCl
Molecular Weight	478.38 g/mol
Synonyms	7-Chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one N1-(2-Hydroxyethyl) Derivative Hydrochloride; Flurazepam N1-Hydroxyethyl Metabolite Hydrochloride; 1-(2-Hydroxyethyl) Flurazepam Hydrochloride; Flurazepam Impurity; Norflurazepam Hydroxyethyl Derivative Hydrochloride; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our N1-(2-Hydroxyethyl) Flurazepam Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research use. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.