Description

3-Phenylglutaric Acid Dimethyl Ester is a high-purity diester derivative of phenylglutaric acid, serving as a versatile and critical synthetic intermediate. Its value lies in providing a protected, reactive scaffold for constructing complex organic molecules with precise stereochemistry. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of chiral drugs and bioactive compounds.
• Organic Synthesis Reagent: Used in reactions such as alkylations, condensations, and cyclizations to introduce the phenylglutarate moiety.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in asymmetric catalysis.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances.
• Academic and R&D: Used in research laboratories for method development and exploring new synthetic pathways.
• Material Science: Potential monomer or cross-linking agent in the development of novel polymers.

Basic Information

Product Name	3-Phenylglutaric Acid Dimethyl Ester
CAS No.	19006-47-4
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	Dimethyl 3-Phenylglutarate; Dimethyl 3-Phenylpentanedioate; 3-Phenylpentanedioic Acid Dimethyl Ester; Pentanedioic Acid, 3-Phenyl-, 1,5-Dimethyl Ester; NSC 3349; 1,5-Dimethyl 3-Phenylpentanedioate
EINECS	Contact for details

Quality Control

Our 3-Phenylglutaric Acid Dimethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.