Description

1,3,4,6-Tetra-o-Acetyl-β-D-Mannopyranose is a key acetylated sugar derivative, serving as a crucial protected intermediate in synthetic carbohydrate chemistry. Its primary value lies in enabling the controlled synthesis of complex oligosaccharides, glycoconjugates, and other bioactive molecules where the mannose moiety is essential. This high-purity building block is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly in the development of novel therapeutics, vaccines, and diagnostic agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex carbohydrate-based drugs, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and neoglycoconjugates for vaccine development and biological studies.
• Oligosaccharide Assembly: Serves as a protected mannosyl donor in automated and solution-phase oligosaccharide synthesis.
• Chemical Biology Probes: Foundation for creating labeled sugar analogs and metabolic probes to study glycosylation pathways.
• Enzyme Substrate/Inhibitor Development: Used to create substrates or inhibitors for glycosidases and glycosyltransferases.
• Fine Chemical Synthesis: Intermediate in the production of specialty surfactants, chiral auxiliaries, and other value-added chemicals.

Basic Information

Product Name	1,3,4,6-Tetra-o-Acetyl-β-D-Mannopyranose
CAS No.	18968-05-3
Molecular Formula	C₁₄H₂₀O₁₀
Molecular Weight	348.30 g/mol
Synonyms	1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose; β-D-Mannopyranose 1,3,4,6-tetraacetate; 2,3,4,6-Tetra-O-acetyl-β-D-mannopyranose (common numbering variation); Tetraacetylmannose; Mannose tetraacetate; Acetylated Mannose; 1,3,4,6-Tetra-O-acetyl-β-D-mannose
EINECS	Contact for details

Quality Control

Our 1,3,4,6-Tetra-o-Acetyl-β-D-Mannopyranose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.