Description

tert-Butyl Pentachlorophenyl Carbonate is a specialized organic carbonate ester, primarily utilized as a key reagent and protecting group intermediate in advanced chemical synthesis. Its value lies in its role as a versatile building block for introducing the tert-butyloxycarbonyl (Boc) group onto sterically hindered or highly electrophilic substrates, where traditional Boc-anhydride may be less effective. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, particularly for the synthesis of complex molecules, peptides, and active ingredients requiring robust protection strategies.

Application

• Pharmaceutical Intermediate: Serves as a Boc-protecting agent for amines in the multi-step synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Chemistry: Used to introduce the tert-butyloxycarbonyl (Boc) protecting group onto amino acids and peptide fragments during solid-phase and solution-phase peptide synthesis.
• Agrochemical Synthesis: Acts as a key reagent in the production of advanced herbicides, fungicides, and insecticides, where specific carbonate intermediates are required.
• Polymer Science: Employed as a monomer or chain-transfer agent in the synthesis of specialized polycarbonates and other functional polymers.
• Organic Synthesis Reagent: Functions as an efficient acylating agent and carbonate donor in various organic transformations, including esterifications and carbonylation reactions.
• Chemical Research: A valuable tool for academic and industrial R&D laboratories exploring new synthetic methodologies and protecting group chemistry.

Basic Information

Product Name	tert-Butyl Pentachlorophenyl Carbonate
CAS No.	18942-25-1
Molecular Formula	C11H9Cl5O3
Molecular Weight	376.45 g/mol
Synonyms	tert-Butyl pentachlorophenyl carbonate; Pentachlorophenyl tert-butyl carbonate; Boc-Pentachlorophenyl Carbonate; BOC-OPcp; (2-Methylpropan-2-yl) pentachlorophenyl carbonate; Carbonochloridic acid, pentachlorophenyl ester, 1,1-dimethylethyl ester; t-Butyl PCP carbonate; tert-Butoxycarbonyl pentachlorophenyl carbonate
EINECS	Contact for details

Quality Control

Our tert-Butyl Pentachlorophenyl Carbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.