Description

17β-(Trimethylsiloxy)-5β-Androstane is a high-purity steroidal intermediate characterized by its trimethylsilyl-protected hydroxyl group. This compound is of significant value in pharmaceutical research and development, serving as a key synthon for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors engaged in steroid chemistry and hormone-related drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of steroidal drugs and hormones.
• Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and novel steroid derivatives.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in steroid analysis.
• Fine Chemical Synthesis: Employed in the production of specialized, high-value steroid compounds for various applications.

Basic Information

Product Name	17β-(Trimethylsiloxy)-5β-Androstane
CAS No.	18899-47-3
Molecular Formula	C22H38O2Si
Molecular Weight	362.63 g/mol
Synonyms	5β-Androstan-17β-ol, 3-trimethylsilyl ether; 17β-Trimethylsiloxy-5β-androstane; 5β-Androstane-17β-ol trimethylsilyl ether; Androstane-17β-ol, trimethylsilyl ether; 17β-(Trimethylsilyloxy)-5β-androstane; 18899-47-3; 5β-Androstan-17β-ol trimethylsilyl ether; 17β-TMS-androstane
EINECS	Contact for details

Quality Control

Our 17β-(Trimethylsiloxy)-5β-Androstane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.