Description

1-Acetyl-3-(Acetyloxy)-7-Chloro-5-(2-Chlorophenyl)-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One is a key benzodiazepine derivative intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters for its role as a versatile building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic candidates.
• Fine Chemical Synthesis: Serves as a precursor in multi-step organic syntheses for complex molecules.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in regulatory testing.

Basic Information

Product Name	1-Acetyl-3-(Acetyloxy)-7-Chloro-5-(2-Chlorophenyl)-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One
CAS No.	18878-17-6
Molecular Formula	C19H14Cl2N2O4
Molecular Weight	405.23 g/mol
Synonyms	7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-1-acetyl-3-acetoxy-2H-1,4-benzodiazepin-2-one; 1-Acetyl-3-acetoxy-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 3-Acetoxy-1-acetyl-7-chloro-5-(o-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1,4-Benzodiazepin-2-one, 1-acetyl-3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-; Diazepam Impurity; Diazepam Related Compound; Contact for further synonyms.
EINECS	Contact for details

Quality Control

Our 1-Acetyl-3-(Acetyloxy)-7-Chloro-5-(2-Chlorophenyl)-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.