Description

7-Chloro-1,3-Dihydro-1-Methyl-5-Phenyl-2-Oxo-2H-1,4-Benzodiazepin-3-Yl Acetate is a high-purity pharmaceutical intermediate and chemical building block of significant importance in synthetic organic chemistry. Its value lies in its role as a key precursor in the research and development of active pharmaceutical ingredients (APIs), particularly within the benzodiazepine class. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and fine chemical synthesis specialists seeking reliable, high-quality intermediates for advanced drug discovery and production processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new therapeutic agents targeting the central nervous system.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex molecular architectures in academic and industrial research settings.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	7-Chloro-1,3-Dihydro-1-Methyl-5-Phenyl-2-Oxo-2H-1,4-Benzodiazepin-3-Yl Acetate
CAS No.	18818-64-9
Molecular Formula	C18H15ClN2O3
Molecular Weight	342.78 g/mol
Synonyms	7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 3-acetate; 3-Acetoxy-7-chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-1-methyl-5-phenyl-3-acetoxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-, 3-acetate; 3-Acetyloxy-7-chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 3-yl acetate; Diazepam Impurity C (Acetyl); Diazepam Related Compound C
EINECS	Contact for details

Quality Control

Our 7-Chloro-1,3-Dihydro-1-Methyl-5-Phenyl-2-Oxo-2H-1,4-Benzodiazepin-3-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical R&D and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under inert atmosphere or with appropriate desiccants to prevent degradation. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.