Description

Bicyclo[2.2.2]Octane-1,4-Dicarboxylic Acid Hemimethyl Ester is a high-purity, synthetically valuable bicyclic organic compound. This chemical serves as a critical advanced intermediate and building block in sophisticated organic synthesis, prized for its rigid, three-dimensional structure. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular frameworks for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring rigid, bridged ring systems to modulate biological activity and pharmacokinetics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the bicyclo[2.2.2]octane scaffold imparts stability and specific bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Advanced Material Monomer: Employed in the production of specialty polymers and resins with enhanced thermal stability, mechanical strength, and unique optical properties.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex natural product analogs and exploring new chemical spaces.
• Cross-linking Agent: Potential use in creating cross-linked polymer networks for coatings, adhesives, and composites due to its di-functional ester groups.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-1,4-Dicarboxylic Acid Hemimethyl Ester
CAS No.	18720-35-9
Molecular Formula	C12H16O4
Molecular Weight	224.25 g/mol
Synonyms	1,4-Bicyclo[2.2.2]octanedicarboxylic Acid Hemimethyl Ester; Bicyclo[2.2.2]octane-1,4-dicarboxylic Acid Monomethyl Ester; 1,4-Bis(methoxycarbonyl)bicyclo[2.2.2]octane (incorrect for hemiester, but a common related search); BCODA Hemimethyl Ester; 1,4-Dicarbomethoxybicyclo[2.2.2]octane (incorrect for hemiester); Methyl Hydrogen Bicyclo[2.2.2]octane-1,4-dicarboxylate
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-1,4-Dicarboxylic Acid Hemimethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.