Description

Trimethylsilyl-L-(+)-Arabinose is a protected derivative of the natural sugar L-arabinose, featuring trimethylsilyl (TMS) groups that enhance its stability and solubility in organic solvents. This modification is critical for its primary role as a versatile chiral building block and intermediate in sophisticated organic synthesis. It is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, enantiomerically pure intermediates for developing active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of nucleoside analogs, antiviral agents, and other bioactive compounds.
• Glycochemistry & Carbohydrate Research: Used in the preparation of complex oligosaccharides, glycoconjugates, and labeled sugar derivatives for biochemical studies.
• Asymmetric Synthesis: Acts as a chiral pool starting material or auxiliary for constructing stereogenic centers in natural products and fine chemicals.
• Agrochemical Development: Employed in the research and production of chiral active ingredients for advanced crop protection products.
• Process Chemistry & Scale-up: Suitable for use in pilot plant and commercial-scale manufacturing where consistent quality and reliable supply are paramount.
• Analytical Standard: Provides a high-purity reference standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	Trimethylsilyl-L-(+)-Arabinose
CAS No.	18623-26-2
Molecular Formula	C14H32O5Si2
Molecular Weight	336.58 g/mol
Synonyms	L-Arabinose, trimethylsilyl derivative; 1,2,3,4-Tetra-O-trimethylsilyl-L-arabinopyranose; TMS-L-Arabinose; (2R,3S,4S,5R)-2,3,4,5-Tetrakis(trimethylsilyloxy)pentanal; Tetra-O-trimethylsilyl-α/β-L-arabinopyranose; L-(+)-Arabinose, TMS derivative; Trimethylsilyl ether of L-arabinose
EINECS	Contact for details

Quality Control

Our Trimethylsilyl-L-(+)-Arabinose is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (Area %)
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.