Description

2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-D-Xylose is a fully protected derivative of the pentose sugar D-xylose, where all hydroxyl groups are silylated with trimethylsilyl (TMS) groups. This modification is critical for its role as a key synthetic intermediate, providing exceptional stability and solubility in organic solvents for complex carbohydrate chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of nucleosides, glycoconjugates, and other bioactive molecules where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: Serves as a protected building block for the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Glycochemistry Research: Essential for the controlled, stepwise construction of complex oligosaccharides and glycoconjugates in academic and industrial R&D.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, chiral ligands, and advanced materials requiring a defined sugar scaffold.
• Agrochemical Development: Acts as a precursor for synthesizing sugar-based bioactive compounds with potential herbicidal or insecticidal properties.
• Process Chemistry: Enables scalable, efficient synthetic routes due to its stability, facilitating multi-step reactions without the need for intermediate deprotection.

Basic Information

Product Name	2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-D-Xylose
CAS No.	18623-22-8
Molecular Formula	C17H42O5Si4
Molecular Weight	438.86 g/mol
Synonyms	D-Xylose, 2,3,4,5-tetrakis-O-(trimethylsilyl)-; Tetrakis-O-trimethylsilyl-D-xylose; 1,2,3,4-Tetrakis-O-trimethylsilyl-D-xylopyranose; Per-O-trimethylsilyl-D-xylose; TMS-D-xylose; D-Xylose per-O-TMS derivative; 18623-22-8; D-Xylose, tetrakis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our 2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-D-Xylose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.