Description

(3A'R,4S,7'S,7A'S)-2,2,2',2'-Tetramethyltetrahydrospiro[[1,3]Dioxolane-4,6'-[1,3]Dioxolo[4,5-C]Pyran]-7'-Ol is a high-purity, complex spirocyclic compound featuring a fused dioxolane-dioxolopyran structure. This molecule serves as a critical chiral building block and protected intermediate in sophisticated organic synthesis, enabling the construction of complex natural products and active pharmaceutical ingredients (APIs). It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require advanced, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates and natural products.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce specific chiral centers.
• Glycoscience Research: Serves as a protected sugar or carbohydrate mimetic precursor in the development of glycosidase inhibitors or glycomimetics.
• Agrochemical Development: Intermediate in the creation of novel, stereospecific pesticides and herbicides.
• Material Science: Potential monomer or precursor for specialized polymers with unique structural properties.
• Academic & Contract Research: Used in methodological development and complex molecule synthesis within R&D laboratories.

Basic Information

Product Name	(3A'R,4S,7'S,7A'S)-2,2,2',2'-Tetramethyltetrahydrospiro[[1,3]Dioxolane-4,6'-[1,3]Dioxolo[4,5-C]Pyran]-7'-Ol
CAS No.	18604-28-9
Molecular Formula	C13H20O6
Molecular Weight	272.29 g/mol
Synonyms	7'-Hydroxyspiro[1,3-dioxolane-4,6'-[1,3]dioxolo[4,5-c]pyran], 2,2,2',2'-Tetramethyl-; Tetramethyltetrahydrospiro[dioxolane-4,6'-dioxolo[4,5-c]pyran]-7'-ol; Spirocyclic dioxolane-dioxolopyranol; (3aR,4S,7'S,7a'S)-Hexahydro-2,2,2',2'-tetramethylspiro[1,3]dioxolane-4,6'-[1,3]dioxolo[4,5-c]pyran]-7'-ol; Protected trihydroxycyclopentane derivative; Chiral spiroketal intermediate.
EINECS	Contact for details

Quality Control

Our (3A'R,4S,7'S,7A'S)-2,2,2',2'-Tetramethyltetrahydrospiro[[1,3]Dioxolane-4,6'-[1,3]Dioxolo[4,5-C]Pyran]-7'-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and optical rotation measurement to ensure high chemical and chiral purity. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.