Description

1,2,3,4-Di-o-Isopropylidene-α-D-Galacturonic Acid Methyl Ester is a high-purity, protected sugar derivative that serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. Its value lies in providing a chemically defined, enantiomerically pure scaffold for constructing complex molecules, ensuring precise stereochemical outcomes. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of nucleoside analogs, antiviral agents, and other complex therapeutic molecules.
• Glycochemistry Research: Used as a protected galacturonic acid derivative for studying carbohydrate metabolism and synthesizing oligosaccharides or glycoconjugates.
• Agrochemical Synthesis: Serves as a building block for creating novel, biologically active compounds with specific stereochemistry for crop protection.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials requiring high stereoselectivity.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and asymmetric catalysis studies.
• Diagnostic Reagent Development: Potential use in creating labeled probes or substrates for enzymatic assays and diagnostic kits.

Basic Information

Product Name	1,2,3,4-Di-o-Isopropylidene-α-D-Galacturonic Acid Methyl Ester
CAS No.	18524-41-9
Molecular Formula	C13H20O7
Molecular Weight	288.29 g/mol
Synonyms	Methyl (3S,4S,5R,6R)-3,4-bis[(2R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,5-dihydroxy-6-methoxyoxane-2-carboxylate; Methyl 1,2:3,4-di-O-isopropylidene-α-D-galactopyranuronate; 1,2:3,4-Di-O-isopropylidene-α-D-galacturonic acid methyl ester; Di-O-isopropylidene galacturonic acid methyl ester; D-Galacturonic acid, 1,2:3,4-di-O-(1-methylethylidene)-, methyl ester, α-D-; Galacturonic Acid Methyl Ester Diacetonide
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Di-o-Isopropylidene-α-D-Galacturonic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent hydrolysis of the protecting groups.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.