Description

3-Azidopropanoic Acid is a versatile bifunctional organic compound featuring both a carboxylic acid and an azide group, making it a valuable click chemistry reagent and a key building block in organic synthesis. Its primary value lies in its ability to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling the efficient and selective formation of 1,2,3-triazole linkages. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors who require reliable, high-purity linkers for peptide modification, polymer functionalization, and probe development.

Application

• Click Chemistry Reagent: A fundamental building block for CuAAC reactions to create triazole-based conjugates.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for introducing functional handles.
• Bioconjugation: Facilitates the labeling and modification of peptides, proteins, and antibodies for diagnostic and therapeutic applications.
• Polymer & Materials Science: Serves as a monomer or cross-linker for creating functional polymers, hydrogels, and surface coatings with tailored properties.
• Chemical Biology Probes: Enables the synthesis of activity-based probes and affinity tags for studying biological processes.
• Agrochemical Synthesis: An intermediate in the development of novel crop protection agents.

Basic Information

Product Name	3-Azidopropanoic Acid
CAS No.	18523-47-2
Molecular Formula	C3H5N3O2
Molecular Weight	115.09 g/mol
Synonyms	3-Azidopropionic Acid; Azidoacetic Acid, Methyl-; β-Azidopropionic Acid; 3-Azidopropansäure (German); Acide 3-azidopropanoïque (French); NSC 401121; 18523-47-2; Propanoic acid, 3-azido-
EINECS	Contact for details

Quality Control

Our 3-Azidopropanoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is highly volatile. Keep away from heat, sparks, open flames, and incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.