Description

N-(Triphenylmethyl)glycine ethyl ester is a protected amino acid derivative featuring a trityl (triphenylmethyl) group on the nitrogen atom. This compound is a crucial building block in organic synthesis, particularly in peptide chemistry, where it serves to protect the amine functionality during complex multi-step reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and other bioactive molecules.

Application

• Peptide Synthesis: As a key intermediate for introducing glycine residues with orthogonal N-terminal protection in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Research: Used in the research and development of active pharmaceutical ingredients (APIs), especially for constructing peptide-based drug candidates.
• Chemical Biology: Employed in the synthesis of modified peptides and probes for studying protein-protein interactions and enzyme mechanisms.
• Combinatorial Chemistry: Serves as a building block in libraries for high-throughput screening to discover new lead compounds.
• Agrochemical Research: Potential intermediate in the synthesis of peptide-inspired crop protection agents.
• Material Science: Can be used in the synthesis of specialized polymers or dendrimers with peptide backbones.

Basic Information

Product Name	N-(Triphenylmethyl)glycine ethyl ester
CAS No.	18514-46-0
Molecular Formula	C23H23NO2
Molecular Weight	345.44 g/mol
Synonyms	Ethyl N-Tritylglycinate; Glycine, N-(triphenylmethyl)-, ethyl ester; Ethyl 2-[(triphenylmethyl)amino]acetate; N-Tritylglycine ethyl ester; Trt-Gly-OEt; NSC 334044; Ethyl (tritylamino)acetate; 2-[(Triphenylmethyl)amino]acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our N-(Triphenylmethyl)glycine ethyl ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and identity tests. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.