Description

(2E)-3-(2-Hydroxyphenyl)-1-Pyridin-3-Ylprop-2-En-1-One is a high-purity, light-sensitive chemical building block with a defined chalcone-like structure. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis and pharmaceutical research. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and neurological disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its bioactive scaffold.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a potential electron-transport or emissive layer material due to its conjugated system.
• Chemical Biology Probe: Utilized in research to study protein-ligand interactions and enzyme inhibition.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialized polymers and coatings.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	(2E)-3-(2-Hydroxyphenyl)-1-Pyridin-3-Ylprop-2-En-1-One
CAS No.	18455-64-6
Molecular Formula	C14H11NO2
Molecular Weight	225.24 g/mol
Synonyms	3-Pyridinyl 2-Hydroxychalcone; 1-(3-Pyridinyl)-3-(2-hydroxyphenyl)-2-propen-1-one; (E)-1-(Pyridin-3-yl)-3-(2-hydroxyphenyl)prop-2-en-1-one; 3'-Pyridyl-2'-hydroxychalcone; 2-Hydroxy-3-pyridylchalcone; 3-(2-Hydroxybenzylidene)-1-(3-pyridinyl)-1-propanone; NSC 403914; Chalcone derivative, 3-pyridyl, 2-hydroxy
EINECS	Contact for details

Quality Control

Our (2E)-3-(2-Hydroxyphenyl)-1-Pyridin-3-Ylprop-2-En-1-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.