Description

Benzyl 2-O,3-o-Isopropylidene-6-Deoxy-α-L-Mannopyranoside Methanesulfonate is a key protected carbohydrate intermediate, specifically a mannose derivative with a benzyl glycoside and an isopropylidene acetal protecting group. This compound is critical for synthetic chemists as it provides a versatile chiral building block for the controlled synthesis of complex oligosaccharides, glycoconjugates, and nucleoside analogs. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced carbohydrate chemistry, medicinal chemistry, and the development of novel therapeutics and diagnostic agents.

Application

• Glycosylation Reactions: Serves as a crucial mannosyl donor or acceptor in the stereoselective synthesis of oligosaccharides and glycopeptides.
• Pharmaceutical Intermediates: Used in the research and development of antiviral, antibacterial, and anticancer drugs that target carbohydrate-mediated biological processes.
• Glycoconjugate Synthesis: A building block for creating glycoconjugates for vaccine development and targeted drug delivery systems.
• Chemical Biology Probes: Employed in the synthesis of labeled carbohydrate probes for studying enzyme mechanisms and carbohydrate-protein interactions.
• Nucleoside Analog Preparation: Acts as a precursor in the synthesis of modified nucleosides with potential therapeutic activity.
• Chiral Pool Synthesis: Provides a source of chiral complexity for the asymmetric synthesis of non-carbohydrate natural products.

Basic Information

Product Name	Benzyl 2-O,3-o-Isopropylidene-6-Deoxy-α-L-Mannopyranoside Methanesulfonate
CAS No.	18422-80-5
Molecular Formula	C₁₇H₂₄O₈S
Molecular Weight	388.43 g/mol
Synonyms	Benzyl 2,3-O-Isopropylidene-6-deoxy-α-L-mannopyranoside Methanesulfonate; Benzyl 2,3-O-Isopropylidene-6-deoxy-α-L-mannopyranoside Mesylate; 6-Deoxy-2,3-O-isopropylidene-α-L-mannopyranosyl Benzyl Methanesulfonate; α-L-Mannose Derivative; Protected Mannoside; Benzyl 2,3-O-(1-Methylethylidene)-6-deoxy-α-L-mannopyranoside Methanesulfonate
EINECS	Contact for details

Quality Control

Our Benzyl 2-O,3-o-Isopropylidene-6-Deoxy-α-L-Mannopyranoside Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.