Description

Di-tert-Butyldichlorosilane is a highly reactive organosilicon compound primarily used as a versatile silylating agent and protecting group precursor. Its value lies in its sterically hindered tert-butyl groups, which confer unique selectivity and stability in demanding synthetic processes. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for the protection of sensitive functional groups and the synthesis of complex silicon-based intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the di-tert-butylsilyl (DTBS) protecting group for alcohols and other nucleophiles in multi-step drug synthesis.
• Agrochemical Production: Used in the manufacture of silicon-containing active ingredients and performance-enhancing additives.
• Advanced Material Precursor: Serves as a building block for synthesizing specialty silicones, silane coupling agents, and silicon-based polymers with tailored properties.
• Organic Synthesis & Catalysis: Employed as a Lewis acid catalyst or ligand modifier in various asymmetric and cross-coupling reactions.
• Surface Modification: Used to functionalize silica, glass, and other inorganic surfaces for improved adhesion or specific chemical properties.
• Laboratory Research: A critical tool in academic and R&D settings for developing new synthetic methodologies and novel organosilicon compounds.

Basic Information

Product Name	Di-tert-Butyldichlorosilane
CAS No.	18395-90-9
Molecular Formula	C8H18Cl2Si
Molecular Weight	213.22 g/mol
Synonyms	Dichlorodi-tert-butylsilane; Di-tert-butylsilyl dichloride; DTBSCl2; (tert-Butyl)2SiCl2; Bis(1,1-dimethylethyl)dichlorosilane; Dichlorobis(tert-butyl)silane; Di-t-butyldichlorosilane
EINECS	242-268-7

Quality Control

Our Di-tert-Butyldichlorosilane is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay by GC or titration and impurity profiling. A detailed Certificate of Analysis (COA) documenting purity, identity, and specific parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Density (at 20°C)	~1.00 g/mL
Refractive Index (n20/D)	~1.450
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.