Description

Diphosphoric Acid Tetrakis(Trimethylsilyl) Ester is a high-purity organosilicon reagent that serves as a versatile silylating agent and protected phosphate source in advanced chemical synthesis. This compound is critical for introducing the trimethylsilyl (TMS) group, which is essential for protecting sensitive functional groups and modifying compound solubility and reactivity. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for synthesizing complex molecules, including nucleotides and functional polymers.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key reagent in the preparation of nucleotide analogs, prodrugs, and other active pharmaceutical ingredients (APIs) requiring phosphate protection.
• Agrochemical Production: Employed in the synthesis of advanced herbicides, insecticides, and plant growth regulators where phosphate ester chemistry is involved.
• Polymer & Material Science: Acts as a monomer or modifying agent in the creation of specialty polymers, flame retardants, and surface-modifying coatings.
• Chemical Research & Development: Serves as a fundamental tool in organic synthesis laboratories for the silylation of alcohols, acids, and other labile functional groups to prevent unwanted side reactions.
• Electrolyte Additive: Investigated for use as a stabilizing additive in advanced lithium-ion battery electrolytes to improve performance and longevity.
• Catalyst & Ligand Preparation: Utilized in the synthesis of organometallic catalysts and ligands for homogeneous catalysis.

Basic Information

Product Name	Diphosphoric Acid Tetrakis(Trimethylsilyl) Ester
CAS No.	18395-45-4
Molecular Formula	C12H36O7P2Si4
Molecular Weight	466.71 g/mol
Synonyms	Bis(trimethylsilyl) Pyrophosphate; Tetrakis(trimethylsilyl) Diphosphate; TMS Pyrophosphate; Pyrophosphoric Acid Tetrakis(trimethylsilyl) Ester; Tetrakis(trimethylsilyl) Pyrophosphate; P,P,P',P'-Tetrakis(trimethylsilyl) Diphosphoric Acid Ester; O,O,O',O'-Tetrakis(trimethylsilyl) Diphosphate; Diphosphoric Acid Tetrakis-O-(trimethylsilyl) Ester
EINECS	Contact for details

Quality Control

Our Diphosphoric Acid Tetrakis(Trimethylsilyl) Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed against stringent in-house specifications, which are aligned with industry best practices for advanced organosilicon reagents. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.